Here are some other benefits of Stendra:47 48 According to an early clinical trial of more than 500 men, close to 3 in 10 using the maximum dosage of Viagra report headaches.

Drug Name Common Side Effects Rare Side Effects Warnings
Viagra Headache, flushing, nasal congestion Vision changes Heart conditions, nitrate meds contraindicated
Cialis Muscle pain, indigestion Prolonged erections (>4 hours) Requires consultation for heart issues
Levitra Dizziness, flushing Sudden vision loss Caution in heart patients

By contrast, just over 1 in 10 men using the 200mg Stendra (highest dosage) report headaches.

4 of the Best Erectile Dysfunction Medications

Rocket Rx has the best prices for sildenafil on the market, and it offers these prices without a major commitment. While low prices from Hims and Strut rely on lower doses or 5-12-month billing cycles, Rocket gets you low prices from orders containing up to 64 tablets. That means you stand to spend a lot less up front to find out if the medication and dose are a fit. For men new to ED medication who want to test the waters while spending as little as possible, BlueChew may be a good place to start, if only because the medication is super convenient to take and because the company offers a free trial. So you can try it out with very little financial risk.

The Best Practice: Treat Erectile Dysfunction with a Urologist

Hims also offers sildenafil in a chew, but only combined with another medication and only at a relatively high combination of doses (which we’ll discuss later in our combination therapy section). However, there are definitely situations in which you might want to opt for Hims’ sildenafil: Hims sildenafil is available in a wider number of doses, making it our top choice for men who find they need to fine-tune or maximize their dosage of sildenafil for the best effect or to reduce side effects. Hims telemedical support is fantastic for men who are dealing with ED alongside efforts to treat premature ejaculation. If you’re one of the many men who already use Hims for hair loss treatment or another service, then it could be convenient to use the same provider for ED treatment as well. Hims offers classic, brand-name Viagra or an authorized generic for men who want it.

Side effects

Hims is also the only company we recommend that sells an authorized generic Viagra. Interestingly, Roman lists their options as “Branded Viagra” and “Generic Viagra.” That second option is actually generic sildenafil — it is not an authorized generic made by Pfizer. Roman lists their sildenafil this way out of the belief that it makes it easier for potential patients to understand that the two drugs are practically identical. Visit our Roman review to learn more. Starts working in as little as 30 minutes Doesn’t cause a particular — but rare — side effect of sildenafil Available in chewable form from BlueChew and Hims While it isn’t the most widely available option from telemedicine providers, vardenafil is an important option for the few men who might not have success taking sildenafil but still want an effective medicine they can take on demand 30-60 minutes before sex. Only about 13% of men using 200mg Stendra experience flushing of the face, compared to 20% of men using the maximum dosage of sildenafil. Heartburn, muscle and back pain, congestion, and vision changes are all less likely with Stendra. Stendra also acts quicker in the body lovegra tablet than others — some studies showed efficacy in as little as 15 minutes.15 This speed makes Stendra a great treatment choice for men who don’t always know when they’ll want to have sex and are happy to take something shortly beforehand.

Product Dosage Quantity + Bonus Price
Kamagra Gold50 mg20 Pills73.17€ 69.69€
Viagra Soft Tabs100mg120 + 8 Pills232.21€ 221.15€
Levitra Generic10mg60 + 6 Pills112.98€ 107.60€
Tadalista Super Active20mg20 + 4 Pills92.35€ 87.95€
Kamagra 100 mg100 mg12 Pills55.64€ 52.99€
Levitra Soft Tabs20mg60 + 4 Pills178.40€ 169.90€
Kamagra Gold100 mg32 Pills121.24€ 115.47€
Kamagra Polo100mg12 Pills60.21€ 57.34€
Viagra Super Active100mg180 + 20 Pills280.97€ 267.59€
Cialis Original20mg12 Pills78.32€ 74.59€

If this describes you, then we recommend Hims Stendra.

Oral Medications for Eresctile Dysfunction

Per-dose cost via Hims is buy super p force jelly cheaper than Viagra Can take it with or without meals Not as affordable as sildenafil or tadalafil Many men prefer to take an ED medication only when they need it rather than at the start of a day when they may or may not have sex. Understandably, these men also want that drug to take effect as quickly as possible and with the lowest chance of side effects. Avanafil (brand-name Stendra) is a newer medication in the landscape of ED treatments. While other ED medications like sildenafil affect enzymes like PDE1 and PDE6 alongside PDE5, Stendra is more micro-targeted to inhibit the specific PDE5 enzyme related to a man’s ability to get and keep an erection. This increases Stendra’s efficacy while reducing its side effect profile. Stendra is also our top choice for couples who enjoy morning sex. Tadalafil taken in the morning can sometimes require about an hour before it is fully effective.

When Erectile Dysfunction Pills Aren't an Option

It’s identical to branded Viagra in every way except that it won’t say “Viagra” on the prescription label. This is one of the least expensive options, though it’s often pricier than generic sildenafil. This is a formula therapeutically identical to branded Viagra but with discrepancies in inactive ingredients, color, shape, and delivery mechanism. Doses are theoretically supposed to be the same, but there are caveats. This is often the least expensive option.

Who should avoid certain ED meds due to health conditions or drug interactions?

Sildenafil is also the active ingredient in Revatio, a drug designed to treat pulmonary arterial hypertension. The drugs are identical in almost every way — they’re even both made by Pfizer — but Revatio is made only in 20mg tablets. Many providers that stock generic sildenafil for ED prefer these 20mg tablets because they allow for more dose flexibility from a single stockpile of pills. A doctor can prescribe 20mg, 40mg, 60mg, or 100mg, and the patient simply takes the corresponding number of 20mg pills. Both branded and generic Viagra come in 25mg tablets, 50mg tablets, and 100mg tablets.

Language matters

If the most common dose is 50mg, then those 100mg doses are going to sit on the shelf, gradually approaching their expiration date and causing providers to lose money. Like tadalafil, sildenafil doses can vary to greater degrees, especially as delivery mechanisms change. For example, BlueChew’s chewable tablets come in 30mg and 45mg doses, neither of which exist in the typical dose ranges for pills. Here’s a quick visual reference detailing which versions of sildenafil our top choices offer: Our recommendation cost of vardenafil here, for most men, is generic sildenafil. Sildenafil is far more economical and allows for better dose tailoring. This experience with tadalafil varies — some men find tadalafil to be effective for a full 36 hours (which would make the prior morning’s dose still effective), while others find its effects wear off in closer to 18 hours. If you are in the latter camp, Stendra will be better for your morning rituals because you can take a dose as you wake up and then be ready for fun in as little as 15 minutes. However, Stendra will cost you significantly more than sildenafil or tadalafil. Hims — our top choice for convenient access to Stendra — offers a monthly subscription for four 100mg Stendra tablets at $210 per month, billed quarterly. If you can afford the cost, this may be the best choice for you. If not, then we’d suggest you explore daily tadalafil.

  • Safety Measures: Avoid combining ED pills with alcohol or certain drugs.
  • Popularity Trends: Sildenafil remains the most common ED drug worldwide.
  • Market Growth: Increasing availability of natural and herbal ED supplements.
  • Consumer Reviews: Many find generic options effective and affordable.
  • Pharmaceutical Innovations: New formulations aim for fewer side effects.
  • Regulated Quality: Importance of purchasing from reputable sources.
  • Cost Considerations: Generic pills reduce treatment expenses.
  • Lifestyle Influence: Combining medication with lifestyle changes enhances results.
  • Medical Supervision: Monitoring vital for long-term management.
  • Cultural Acceptance: Growing societal openness to ED treatments.
  • Ongoing Research: New drugs and therapies continually under study.

There are three standard dosage options for Stendra: Both the 100mg and 200mg dosages take effect in about 15 minutes.

  • Herbal Viagra: Natural alternative with herbal extracts claiming to boost erections.
  • Rhodiola Rosea: Herb thought to improve stamina and reduce fatigue affecting performance.
  • Ginseng: Traditionally used to enhance libido and erectile function.
  • Maca Root: Plant-based supplement purported to increase libido naturally.
  • L-Arginine: Amino acid that improves nitric oxide production for better blood flow.
  • Horny Goat Weed: Herbal supplement believed to treat ED and enhance libido.
  • Tribulus Terrestris: Used to improve sexual function and testosterone levels.
  • Muira Puama: Historically used as a libido booster and for erectile issues.
  • Yohimbine: Extract used to improve blood flow and nerve function.
  • Tongkat Ali: Traditional herb to boost testosterone and sexual performance.
  • Ashwagandha: Adaptogen that may reduce stress and improve sexual stamina.

Sublingual dose requires no water to take FDA-approved for use in Parkinson’s patients May cause fainting in a small fraction of users Nausea is a common initial side effect Hard to find outside Rugiet’s blended ED treatment Apomorphine has been used since the 19th century as everything from a sedative to an aid in kicking heroin addiction, and it’s currently FDA-approved for treating Parkinson’s disease. However, multiple studies indicate its potential as a treatment for ED.16 The name can be a source of confusion since most people outside the medical professions would likely hear the “morphine” part and assume opioid properties.

Staxyn (vardenafil)

Studies show that vardenafil behaves the same way in the body as sildenafil, with one known exception. A rare side effect of sildenafil is an alteration in color perception due to the drug’s inhibition of PDE6 in addition to PDE5.13 Vardenafil is somewhat more selective in this regard, having no known effect on PDE6 and, therefore, no known effect on color perception. And while vardenafil is less thoroughly researched than sildenafil, there are still numerous studies looking at thousands of users over nearly two decades, so its safety and efficacy are without question.14 For a while, BlueChew was the only provider among our top picks to offer vardenafil, but Hims has included it in its recent development of chewable mint tablets. Despite not typically being a daily medication, Hims offers a 30-day supply of vardenafil that bears the same low price as its daily tadalafil. As a result, you can get 8.5mg vardenafil chews from Hims for significantly less than you can from BlueChew.

Erectile dysfunction care at Mayo Clinic

Hims’ low price on vardenafil reflects their pricing for a 150-day supply. If you don’t want to stockpile vardenafil like that, the next-lowest price per dose you can get from Hims on smaller quantities of vardenafil is $6, which is more expensive than even the highest price per dose from BlueChew. BlueChew's free trial still makes it the best starting place for men new to ED treatments. After that, you can use the low price of Hims’ 30, 90-, and 150-day supplies to stock up on vardenafil chews at a lower cost (as long as you plan to finish your supply before it expires). But men seeking smaller quantities for as-needed use should stick with BlueChew. But apomorphine doesn’t bind to opioid receptors and is nonaddicting.

  • Viagra (Sildenafil): The most well-known ED pill that increases blood flow to the penis for reliable erections.
  • Cialis (Tadalafil): Offers long-lasting effects up to 36 hours, suitable for spontaneous sexual activity.
  • Levitra (Vardenafil): Works quickly and lasts around 4-5 hours, effective for men with diabetes-related ED.
  • Stendra (Avanafil): Rapid onset within 15 minutes, with fewer side effects, ideal for on-demand use.
  • Kamagra: An affordable alternative to branded pills, containing Sildenafil, but quality varies.
  • Spedra: Fast-acting ED medication with quick relief, effective for those needing urgent results.
  • Cenforce: Generic Sildenafil option, often at a lower price, with similar effectiveness.
  • Vidalista (Tadalafil): Suitable for daily or as-needed use, with extended duration.
  • Malegra: Generic Sildenafil-based pills, popular for affordability and effectiveness.
  • Tadalista: Tadalafil-based, used for ED and prostate issues, with long duration effects.
  • Eriacta: Generic Sildenafil tablets, trusted as a cost-effective ED solution.

For Parkinson’s patients, apomorphine is delivered via subcutaneous injection at doses often higher than those used in ED treatment. Studies into its use for Parkinson’s revealed intense nausea as a potential side effect — often to the point that doctors would have to prescribe an antiemetic to deal with nausea and vomiting.

  • Natural doesn't always mean safe; herbal supplements can interact with medications.
  • FDA-approved prescription drugs have proven efficacy and safety profiles from clinical trials.
  • Over-the-counter "herbal Viagra" products are often adulterated with prescription drugs.
  • Supplements are not strictly regulated for purity, potency, or accuracy of labeling.
  • Placebo effect can account for perceived benefits from some alternative ED remedies.
  • Evidence-based medicine relies on large, randomized, controlled clinical trials.
  • Anecdotal reports and testimonials are not reliable substitutes for scientific evidence.
  • Consult a healthcare provider before starting any new supplement, especially with heart conditions.

ED patients taking apomorphine as a sublingual film — or, in the case of Rugiet, a lozenge — may also experience some nausea, but this appears to decline with regular use.17 Apomorphine appeared on target to become a viable alternative to Viagra in 2000, but the manufacturers behind its two branded forms intended for ED patients pulled it from FDA consideration despite what appeared to be a sure path to approval. They cited the need for further study, particularly into the drug's interaction with nitrates and its potential to cause fainting in less than 0.2% of trial participants.