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It’s not recommended to take multiple ED medications together, including Viagra and Cialis. Taking them together could increase the risk of side effects. Talk with a healthcare professional to figure out the best ED treatment(s) for you. No, there isn’t a way to completely flush Cialis out of your system. The best thing to do is wait for your body to clear it out naturally. There are certain medications, such as rifampin (Rifadin) and carbamazepine (Tegretol), that make your body clear Cialis out more quickly.
| Parameter | Value | Notes |
|---|---|---|
| Absorption | Peak plasma concentrations in 2 hours | Food slightly delays absorption |
| Half-life | Approx. 17.5 hours | Allows once daily dosing |
| Metabolism | Liver (CYP3A4 enzyme) | No dose adjustment needed in mild impairment |
| Excretion | Feces (61%), Urine (36%) | -- |
But the full effects of those medications on Cialis aren’t well known.
| Active Ingredient | Dosage | Inactive Components | Tablet Shape | Color |
|---|---|---|---|---|
| Tadalafil | 10 mg | Lactose, Crospovidone | Round | Yellow |
| Tadalafil | 10 mg | Corn starch, Sodium Starch Glycolate | Round | Yellow |
| Tadalafil | 10 mg | Silicon dioxide, magnesium stearate | Round | Yellow |
| Tadalafil | 10 mg | Cellulose, gelatin | Round | Yellow |
No, Cialis doesn’t make you last longer. If you’re climaxing earlier than you’d like during sex (premature ejaculation), Cialis won’t make a difference. You can practice delaying orgasm by using the start-stop technique or the squeeze technique.
- Beyond erectile dysfunction, Tadalafil is approved to treat benign prostatic hyperplasia (BPH).
- For BPH, it helps relax smooth muscles in the prostate and bladder.
- This can improve urine flow and reduce symptoms like frequent urination.
- A single daily dose can treat both ED and BPH simultaneously.
- The mechanism for treating BPH is similar to its effect on blood vessels.
- Not all ED medications are approved for treating BPH; Tadalafil is unique in this.
- Discuss all your symptoms with a doctor to see if this dual benefit applies.
- The dose for BPH treatment is often a daily 5mg tablet.
Certain antidepressants, such as sertraline (Zoloft), can also prolong time before ejaculation as an off-label use, meaning it’s not an FDA-approved use for sertraline. Efficacy and safety of tadalafil once-a-day versus tadalafil on-demand in patients with erectile dysfunction: A systematic review and meta-analyses.
Apcalis SX20 Tablet price and minimum order quantity
If so, be sure to take it at the same time every day — no matter when you plan on having sex. Whichever way you take Cialis, don’t take more than one dose per day. This helps prevent unnecessary risk and side effects. Combining ED medications like Cialis with high blood pressure medications can cause blood pressure that’s too low. One of Cialis’ side effects is lower blood pressure, so this can be a problem when paired with other blood pressure-lowering medications.
What are you using this medicine for?
This is especially true when Cialis is paired with a nitrate medication. You should avoid this combination since these medications have a high risk of causing dangerously low blood pressure. Other medications and foods can also interact with Cialis. They may lead to additional side effects. It’s always a good idea for your pharmacist and all prescribers to have an up-to-date list of all the medications and supplements you take.
Off-label use for Cialis
That way, they can minimize any interactions. Some of the more common Cialis side effects include: Side effects can slightly differ if you’re taking Cialis daily. In addition to what’s mentioned above, these side effects are more likely to occur with daily use: These side effects are usually mild and go away on their own. But if they don’t, you can usually treat them at home. For example, headaches can often be managed by drinking more water or taking an over-the-counter (OTC) pain reliever, such as acetaminophen (Tylenol). Tadalafil population pharmacokinetics in patients with erectile dysfunction. Brand Name: Apcalis Sx 20 Tablets Active Ingredient: Tadalafil 20mg Manufacturer: Ajanta Pharma Form: Tablets Packing: Pack of 4 Tablets Strength: 20mg Oddway International supports transactional procurement for importers, licensed distributors, hospitals, and institutional buyers seeking a reliable Apcalis SX20 Tablet supplier.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Apcalis SX Oral Jelly | 20mg | 50 + 6 Sachets | 146.39€ 139.42€ | |
| Apcalis SX Oral Jelly | 20mg | 120 + 13 Sachets | 280.38€ 267.03€ | |
| Kamagra Soft Tabs | 100mg | 84 + 4 Pills | 233.05€ 221.95€ | |
| Super Kamagra | 160 mg | 32 + 4 Pills | 218.25€ 207.86€ | |
| Apcalis SX Oral Jelly | 20mg | 10 Sachets | 58.75€ 55.95€ | |
| Levitra Original | 20mg | 34 + 2 Pills | 188.51€ 179.53€ | |
| Viagra Generic | 50mg | 90 + 6 Pills | 107.37€ 102.26€ | |
| Apcalis SX Oral Jelly | 20mg | 30 + 5 Sachets | 141.84€ 135.09€ | |
| Apcalis SX Oral Jelly | 20mg | 70 + 7 Sachets | 184.98€ 176.17€ | |
| Kamagra 100 mg | 100 mg | 32 Pills | 121.24€ 115.47€ | |
| Cialis Generic | 20mg | 270 + 10 Pills | 335.21€ 319.25€ | |
| Levitra Soft Tabs | 20mg | 360 + 20 Pills | 682.21€ 649.72€ | |
| Viagra Oral Jelly | 100mg | 220 + 18 Sachets | 562.28€ 535.50€ | |
| Kamagra Polo | 100 mg | 60 + 4 Pills | 189.39€ 180.37€ | |
| Apcalis SX Oral Jelly | 20mg | 17 + 4 Sachets | 95.52€ 90.97€ |
We coordinate compliant sourcing for bulk Apcalis SX20 Tablet requirements, subject to local regulations, prescription medicine controls, and importer documentation. Additionally, our team manages brand verification, export paperwork, and shipment planning for regulated and semi-regulated markets. As a trusted Indian Pharmaceutical exporter, Oddway International works with approved supply channels and requested brands where permitted. Buyers can request commercial quotations, documentation support, and destination-specific guidance for institutional procurement. Therefore, procurement teams can evaluate timelines and compliance requirements before issuing purchase confirmation.
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But know that it can take up to 2 hours for the full effects to kick in. Studies also show that Cialis is not affected by the timing of meals. In other words, you can take Cialis with or without food — it won’t affect how fast it works. By comparison, Viagra also begins to work within 30 minutes. But its maximum effects usually set in after about 45 minutes to 1 hour.
Dosage for erectile dysfunction (ED)
Other PDE5 inhibitors start working even faster. Vardenafil can start working in about 15 minutes, and avanafil (Stendra) starts working in under 15 minutes. Similarly to Viagra, their maximum effects also tend to appear in under an hour. The effects of Cialis last longer than the effects of Viagra. Viagra usually lasts for up to 5 hours.
Drug forms and administration
That doesn’t mean every time you take Cialis, you’ll have an erection lasting a full day and a half. Instead, Cialis can help you achieve an erection throughout those 36 hours. How long Cialis lasts is a reason why some people prefer it over other ED medications; it allows for more spontaneous sexual activity. If your erection lasts longer than 4 hours, even if it’s not painful, that’s considered a medical emergency. Call 911 or go to the nearest ER if you experience a prolonged erection. Apcalis SX20 Tablet belongs to the phosphodiesterase type 5 inhibitor drug class and is commonly associated with tadalafil-based erectile dysfunction therapy, where approved by local authorities.
| Precaution / Interaction | Potential Effect | Advice |
|---|---|---|
| Concomitant use with nitrates | Severe hypotension | Avoid combination |
| Use with alpha-blockers | Risk of orthostatic hypotension | Titrate dose carefully |
| Severe hepatic impairment | Increased drug levels | Use with caution, lower doses |
| Grapefruit juice | Alters drug metabolism | Avoid intake during use |
| Cardiovascular conditions | Risk of adverse events | Consult doctor before use |
It should be used only under qualified medical supervision and according to applicable prescription rules. The product is not suitable for promotional, non-medical, or unsupported patient-facing claims. Potential side effects may include headache, flushing, nasal congestion, dizziness, indigestion, back pain, or muscle discomfort.
- The development of Tadalafil was a significant advancement in ED treatment.
- It was first approved by the FDA for medical use in the United States in 2003.
- Its long duration of action differentiated it from earlier PDE5 inhibitors.
- Generic versions became available after the patent on the brand drug expired.
- This increased accessibility and affordability for patients worldwide.
- Ongoing research continues to explore new applications for PDE5 inhibitors.
- The medication has improved the quality of life for millions of men.
- It remains a first-line treatment option recommended by urologists.
Precautions apply for patients with cardiovascular disease, liver or kidney impairment, low blood pressure, recent stroke, or vision-related disorders. Warnings also apply with nitrates, riociguat, certain alpha-blockers, antihypertensives, strong CYP3A4 inhibitors or inducers, and excess alcohol. The Apcalis SX20 Tablet price is shared through a formal quotation after confirming destination country, requested brand, documentation needs, and order route. The Apcalis SX20 Tablet cost may vary due to manufacturer terms, export documentation, freight mode, and regulatory requirements. However, Oddway International does not publish medical product pricing without verified B2B enquiry details. Minimum order quantity is confirmed case by case for wholesale, institutional, export, or Named Patient Supply requests. Moreover, the final Apcalis SX20 Tablet price and MOQ appear in the proforma invoice only after buyer verification, product confirmation, and route assessment. This process helps importers plan compliant procurement without unsupported assumptions. Apcalis SX20 Tablet is generally requested in 20 mg strength, subject to brand, manufacturer, and destination approval. For Apcalis SX20 Tablet India sourcing, packaging, labeling, inserts, and commercial presentation depend on the requested brand and market authorization. Furthermore, buyers can ask for documentation that supports customs review and institutional receiving procedures. For bulk Apcalis SX20 Tablet procurement, Oddway International coordinates product verification before export processing.
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There are two ways to take Cialis for ED: Take a higher-dose tablet on an as-needed basis — at least 30 minutes before you plan to have sex. Take a higher-dose tablet on an as-needed basis — at least 30 minutes before you plan to have sex. Take a lower-dose tablet at the same time every day, even if you don’t plan on having sex that day. The 10 mg tablet is usually recommended for as-needed use, though some people with ED might find that a lower (5 mg) or higher (20 mg) dose works better for them. The 2.5 mg and 5 mg tablets are more common choices for daily, scheduled doses.
2. Cialis can last for up to 36 hours
One of the benefits of daily Cialis doses is that they provide continuous medication levels, allowing for greater spontaneity in sexual activity without the need to plan around medication timing. According to several studies, there’s no difference in how well Cialis works or side effects between these two methods. However, daily Cialis isn’t recommended if you have severe kidney problems. Keep in mind: With both methods, know that finding the right dose might take some trial and error. Make sure to tell your prescriber if your Cialis dose isn’t effective enough for you or if you’re having side effects.
Comparison with actions of other PDE5 inhibitors
Your prescriber might increase or decrease your dose, or they might switch you to a different ED medication altogether. If you take Cialis as needed, be sure to give yourself plenty of time before sex. It can take about 2 hours for Cialis’ maximum effects to kick in. You can’t make it work faster after you’ve taken a dose. If as-needed doses aren't working for you, your prescriber might want you to take a lower-dose tablet on a daily basis instead. Packaging is supplied according to approved commercial presentation and buyer requirements where permitted. Consequently, importers receive clearer visibility on pack details, documentation needs, and shipment feasibility before completing procurement.
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For indigestion and acid reflux, OTC antacids like Tums (calcium carbonate) can help. If these side effects are still bothering you despite your best efforts to treat them, talk to your prescriber. They might lower your dose or explore other options for treating your ED. Rare but serious side effects of Cialis may include: If any of these happen to you, stop taking Cialis and go to the nearest ER right away. There are ways to save on Cialis, which is available as both a generic- and brand-name medication.
Cialis and foods
Save with GoodRx: GoodRx can help you save over 80% off the average retail price of the generic version. Generic Cialis’ price at certain pharmacies is as low as apcalis oral jelly 20 mg $18.00 for 30 tablets with a free GoodRx discount. An equivalent dose of the brand-name product may cost as little as $855.84 with a free GoodRx discount. Save with GoodRx Care Direct: Get generic Cialis delivered directly to your door starting at $21 per month. Save with a patient assistance program: If you’re uninsured or underinsured, you may be eligible for Cialis’ patient assistance program, which offers the medication free of charge.